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Dr John Briffa's blog, A Good Look at Good Health — writing on food, cholesterol, weight, energy and the science behind everyday health, from the drbriffa.com archive. Filter by topic, browse by category, or search the library.

How to design a trial to ensure you don’t get the result you don’t want Food and Medical Politics

How to design a trial to ensure you don’t get the result you don’t want

Earlier this month I wrote a post that focused on a trial involving the cholesterol-reducing drug ezetimibe. Ezetimibe works in a different way to statins (the most commonly prescribed cholesterol-reducing medication). While statins block cholesterol’s production in the liver, ezetimibe block its absorption from the gut. When you add ezetimibe to a statin (there’s a […]

June 29, 2011· 4 min read· Dr Briffa
Formaldehyde officially ‘cancer-causing’ (and the common foodstuff that increases our exposure to this chemical) Food and Medical Politics

Formaldehyde officially ‘cancer-causing’ (and the common foodstuff that increases our exposure to this chemical)

Reuters recently reported here that the US Government has added the chemical formaldehyde to its official list of cancer-causing agents. You’ll learn from the Reuters piece that formaldehyde is found in things like some plastics and embalming fluid. But what you won’t learn from the piece is that it can be derived from our diet […]

June 15, 2011· 3 min read· Dr Briffa
Podcast – 10th June 2011 Cholesterol and Statins

Podcast – 10th June 2011

Cholesterol drug ezetimibe appears to do more harm than good, screening for ovarian cancer doesn’t work, and vitamin D linked with reduced risk of infection. For RSS feeds, click on http://www.podcastmachine.com/podcasts/8966 and then the ‘RSS feeds’ button to the right. For help regarding the playing, downloading and subscribing of the podcasts, click here.

June 10, 2011· 1 min read· Dr Briffa
Cholesterol-reducing drug ezetimibe appears to do more harm than good Cholesterol and Statins

Cholesterol-reducing drug ezetimibe appears to do more harm than good

Cholesterol is said to cause heart disease (I’m not so sure, myself), and a mainstay of treatment here is a class of drugs known as ‘statins’ that reduce the rate at which cholesterol is manufactured in the liver. Statins have been used in medicine for over 20 years, but more recently has seen the development […]

June 10, 2011· 3 min read· Dr Briffa
Ovarian cancer screening doesn’t work Food and Medical Politics

Ovarian cancer screening doesn’t work

For many, cancer screening has obvious appeal. Detecting the disease through screening will generally mean an earlier diagnosis, and earlier treatment should, by rights, lead to better outcomes. Well, that the theory anyway. In practice, though, we know that screening is most certainly not as effective as we might imagine. For example, mammography has been […]

June 8, 2011· 3 min read· Dr Briffa
How did this man get to live with type 1 diabetes for more than 80 years? Diabetes/Metabolic Syndrome

How did this man get to live with type 1 diabetes for more than 80 years?

I came across this interesting story the other day. It concerns an American, Bob Krause, who has just turned 90. Nothing to extraordinary about that, perhaps, in these days of enhanced longevity. What makes the story interesting is that when he was 5 years old, Bob was diagnosed with type 1 diabetes. This is condition […]

May 31, 2011· 4 min read· Dr Briffa
Podcast – 27th May 2011 Brain and Behaviour

Podcast – 27th May 2011

Red meat and colon cancer, melanoma doctor urges us to get out in the sun, could hunger and low blood sugar have something to do with disharmony in the home? For RSS feeds, click on http://www.podcastmachine.com/podcasts/8966 and then the ‘RSS feeds’ button to the right. For help regarding the playing, downloading and subscribing of the […]

May 26, 2011· 1 min read· Dr Briffa
Melanoma doctor urges us to get more sun! Food and Medical Politics

Melanoma doctor urges us to get more sun!

I almost fell of office chair yesterday when I read this article in the UK’s Daily Mail by oncologist (cancer specialist) Professor Angus Dalgleish. Professor Dalgleish has a particular interest in malignant melanoma. In the piece, he draws our attention to the links between vitamin D and cancer, including the link between low vitamin D […]

May 26, 2011· 2 min read· Dr Briffa
Podcast – 20th May 2011 Food and Medical Politics

Podcast – 20th May 2011

Vitamin D boosts wellbeing in the elderly, the nonsense of ‘normal’ ranges, and why the ‘broadening of disease’ can be good business for drug companies but leave ordinary people worse off. For RSS feeds, click on http://www.podcastmachine.com/podcasts/8966 and then the ‘RSS feeds’ button to the right. For help regarding the playing, downloading and subscribing of […]

May 20, 2011· 1 min read· Dr Briffa
Broadening the definition of ‘disease’ may be good business for drug companies but can leave ordinary people worse off Food and Medical Politics

Broadening the definition of ‘disease’ may be good business for drug companies but can leave ordinary people worse off

Last September one of my blogs reported on a piece in the British Medical Journal in which journalist, authors and patient advocate Ray Moynihan alerted us to the potentially unhealthy links between the pharmaceutical industry and doctors who set health policy. Specifically, Mr Moynihan’s concern was the definition of disease is being widened, and this […]

May 20, 2011· 4 min read· Dr Briffa